Antibiotic stewardship with the help of B·R·A·H·M·S PCT (Procalcitonin)


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The overuse of antibiotics is a global problem but the B·R·A·H·M·S Procalcitonin assay can help guide the judicious use of antibiotics.

The problem: Antibiotic resistance is an increasing threat to public health

pct-antibiotic-stewardship-unnecessary-prescriptionsData shows that 1/3 of antibiotic prescriptions are unnecessary *Centers for Disease Control and Prevention (CDC), Press Release, May 3, 2016 > read moreAntibiotics (ABx) are a limited resource. At the current pace of injudicious use, all antibiotics will soon become ineffective. The emergence and spread of antibiotic resistant bacteria harm individuals and societies worldwide by causing:

  • Prolonged illnesses
  • Higher health care expenditures
  • Greater risk of death


B·R·A·H·M·S PCT (Procalcitonin) supports responsible use of antibiotics

Due to its high sensitivity and specificity B·R·A·H·M·S PCT safely supports responsible use of antibiotics to prolong their effectiveness. Strong evidence supports the reduction of antibiotics using PCT-guided antibiotic stewardship protocols. Antibiotic Guidance with B·R·A·H·M·S PCT could help reduce the initial antibiotic prescription rates and also the antibiotic treatment duration.  

Surviving Sepsis Campaign: “We suggest that measurement of procalcitonin levels can be used to support shortening the duration of antimicrobial therapy  in sepsis patients.“   Source: International Guidelines for Management of Sepsis and Septic Shock, 2016 


Benefits of B·R·A·H·M·S PCT in the fight against antibiotic resistance

B·R·A·H·M·S Procalcitonin is an effective tool to safely reduce antibiotic exposure in patients. Strong evidence from reproducible, randomized clinical trials with more than 10,000 patients supports the effectiveness of PCT-guided antibiotic stewardship protocols. It has a proven utility across diverse clinical settings: ICU, ED, Pediatrics, Neonatology, Surgery.


The benefits of PCT-guidance in antibiotic therapy

PCT-guidance of AB therapy has the potential to

  • Reduce initial prescription rates
  • Shorten treatment durations
  • Save overall treatment costs

In addition to other clinical criteria B·R·A·H·M·S Procalctionin supports the decision making, be it for starting antibiotic therapy or its safe discontinuation. As a consequence, a B·R·A·H·M·S PCT-guided algorithm helps to reduce prescriptions, tailor the therapy duration to individual patient needs and finally supports to save costs.

Antibiotic Guidance with B·R·A·H·M·S PCT could help preserve the effectiveness of antibiotics for future generations.


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